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GlucaGen®
Zegalogue®
and insulins

GlucaGen® & insulins
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GlucaGen® & insulins
GlucaGen®
insulins

GlucaGen®

HypoKit® (glucagon) for injection, 1 mg/mL

Before Reconstitution
The GlucaGen® package may be stored up to 24 months at controlled room temperature (68ºF-77°F/20°C-25°C) prior to reconstitution. Avoid freezing GlucaGen® and protect it from light by keeping it in the original package. GlucaGen® should not be used after the expiration date on the vials.6

 

After Reconstitution:
Reconstituted GlucaGen® should be used immediately. Discard any unused portion. If the solution shows any sign of gel formation or particles, it should be discarded.6

 

After the product is manufactured, Novo Nordisk Inc. stores and transports GlucaGen® HypoKit® under refrigerated conditions (36°-46°F/2°-8°C) since maintaining controlled room temperature conditions may be difficult during shipping. Refrigerating the product will not damage it; however, freezing of the product should be avoided.6

Zegalogue®

(dasiglucagon) injection 0.6 mg/0.6 mL

Storage and Stability

Store Zegalogue® in a refrigerator, 2° C to 8° C (36° F to 46° F). Keep away from the cooling element and do not freeze. Zegalogue® can be kept at room temperature between 20° C to 25° C (68° F to 77° F) for up to 12 months. Record the date when the product was removed from the refrigerator in the space provided on the protective case. 

 

Do not return the product to the refrigerator after storing at room temperature. Store in the provided protective case and protect from light. Discard Zegalogue® after the end of the 12-month period at room temperature storage, or after the expiration date stated on the product, whichever occurs first. 

Insulins

Unused (unopened) insulin vials, devices, or cartridges inadvertently left at room temperature can be returned to refrigeration but must be used within designated days of initially being stored at room temperature (see Tables 1 and 2). Products not used within the listed time periods should be discarded.

Table 1. Recommended Storage Conditions for Insulin Analogs7-11

Product

Before First Use

After First Use

Room Temperature
(below 86°F)a,b

Refrigerated
(36°F - 46°F)

Room Temperature
(below 86°F)a

Refrigerated
(36°F - 46°F)

NovoLog® vial (insulin aspart) injection

28 Days

Until expiration date

28 Days

28 Days

NovoLog® FlexPen® (insulin aspart) injection

28 Days

Until expiration date

28 Days

N/Ac

NovoLog® FlexTouch®d (insulin aspart) injection

28 Days

Until expiration date

28 Days

N/Ac

NovoLog® PenFill® (insulin aspart) injection

28 Days

Until expiration date

28 Days

N/Ac

NovoLog® Mix 70/30 vial (70% insulin aspart protamine and 30% insulin aspart) injectable suspension

28 Days

Until expiration date

28 Days

28 Days

NovoLog® Mix 70/30 FlexPen® (70% insulin aspart protamine and 30% insulin aspart) injectable suspension

14 Days

Until expiration date

14 Days

N/Ac

Fiasp® vial (insulin aspart) injection

28 Days

Until expiration date

28 Days

28 Days

Fiasp® FlexTouch® (insulin aspart) injection

28 Days

Until expiration date

28 Days

28 Days

Levemir® vial (insulin detemir) injection

42 Days

Until expiration date

42 Days

42 Days

Levemir® FlexTouch® (insulin detemir) injection

42 Days

Until expiration date

42 Days

N/Ac

Tresiba® U-100 and U-200 FlexTouch® (insulin degludec) injection

56 Days

Until expiration date

56 Days

56 Days

aUnrefrigerated products should be discarded if not used within the time periods listed, whether or not they have been punctured or are in-use.
bUnused (unopened) FlexTouch®, FlexPen® and NovoLog® PenFill® inadvertently left at room temperature can be returned to refrigeration but must be used within designated days of initially being stored at room temperature.
cOnce in use, should be stored at room temperatures below 86ºF.
dNovoLog® FlexTouch® is not currently available in the United States.

Table 1. Recommended Storage Conditions for Insulin Analogs7-11

Product

Before First Use

After First Use

Room Temperature
(below 77°F)a,e

Refrigerated
(36°F - 46°F)

Room Temperature
(below 77°F)a

Refrigerated
(36°F - 46°F)

Novolin® 70/30 (70% human insulin isophane suspension and 30% human insulin) injection

42 Days

Until expiration date

42 Days

N/Ag

Novolin® N NPH (isophane insulin human suspension)

42 Days

Until expiration date

42 Days

N/Ag

Novolin® R (insulin human) injection

42 Days

Until expiration date

42 Days

N/Ag

eUnused (unopened) product inadvertently left at room temperature can be returned to refrigeration but must be used within designated days of initially being stored at room temperature.
fReliOn® brand - manufactured by Novo Nordisk and sold exclusively at WalMart and Sam's Club Pharmacies.
gOnce in use, Novolin® vials and Novolin®/ReliOn® vials should not be refrigerated.

See what to do when products are exposed to freezing or other conditions.

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questions &
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References

1. Ozempic® Prescribing Information. Plainsboro, NJ: Novo Nordisk.
2. RYBELSUS® Prescribing Information. Plainsboro, NJ: Novo Nordisk Inc.
3. Saxenda® Prescribing Information. Plainsboro, NJ: Novo Nordisk Inc.
4. Victoza® Prescribing Information. Plainsboro, NJ: Novo Nordisk Inc.
5. Wegovy™ Prescribing Information. Plainsboro, NJ: Novo Nordisk Inc.

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