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Type 2 Diabetes

Explore facts and recommendations for pharmacological treatments for type 2 diabetes.

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Early Initiation of Oral Semaglutide (POSTER)

Summary of a post hoc analysis evaluating early initiation of oral semaglutide on glycemic efficacy, body weight and achievement of targets in the PIONEER 1 trial

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Effect of Semaglutide 2.0 mg vs 1.0 mg on HgbA1c and Body Weight (POSTER)

Summarizes the effect of semaglutide 2.0 mg vs 1.0 mg on HgbA1c and body weight in pre-specified baseline HgbA1c and BMI subgroups.

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ADA Standards of Medical Care in Diabetes 2023: Use of Glucose-lowering medications in the management of T2D (Poster)

An infographic of the 2023 American Diabetes Association (ADA) Standards of Medical Care in Diabetes referencing Figure 9.3 on the use of glucose-lowering medications in the management of Type 2 Diabetes.

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The Unmet Needs for Insulin Requiring Patients (Poster)

Explains barriers to daily insulin therapy and the benefit of a once-weekly dosing approach.

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Cardiovascular Risk Reduction and Primary Prevention Recommendations (Poster)

A review of the 2020 ACC Expert Consensus Pathway and 2021 AHA/ASA guidelines for the prevention of stroke. Also includes patient and clinician considerations for initiating drug therapy with demonstrated CV benefit.

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GLP-1 RAs and Cardiovascular Outcomes Trials (Poster)

A summary of key CV outcomes of GLP-1RAs on MACE endpoints and CV risk factors. Also highlights the possible mechanism of CV benefits and considerations for drug initiation and monitoring

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ADA/KDIGO Consensus Report - 2022 (Poster)

Treatment algorithm for selecting glucose-lowering medication for patients with type 2 diabetes and chronic kidney disease.

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ADA Standards of Medical Care in Diabetes – 2023

Algorithms and updates from the 2023 guidelines.

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Using GLP-1 RAs in Practice: A Quick Guide (IME Content)

This quick guide summarizes the effects of GLP-1 RAs and offers counseling points for practical application of patient selection by HCPs at point of care.

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Get Smart: Leveraging New Technologies to Optimize Diabetes Management (IME Content)

Review of continuous glucose monitoring, various insulin delivery methods and associated ADA, EASD and AACE guidance. Also highlights patient and provider barriers to the use of diabetes technology.

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Contemporary Diabetes Management With Smart Technology: Case Studies in Continuous Glucose Monitoring (IME Content)

Various case studies to explore the use of Continuous Glucose Monitoring.

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Smart Technology for Diabetes Management: Advances for Insulin Delivery Methods (IME Content)

Comprehensive overview of various insulin delivery devices.

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type 2 diabetes Video

Semaglutide Injection Mechanism of Action

This video discusses the mechanism of action and mechanism of protraction of the semaglutide injection.

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Oral Semaglutide Mechanism of Action

This video discusses the mechanism of action of oral semaglutide.

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Oral Semaglutide Mechanism of Absorption

This video discusses the mechanism of absorption of oral semaglutide.

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Pharmacokinetic, Pharmacodynamic (PK/PD) & Dosing Considerations for Oral Semaglutide

This video describes PK/PD considerations that can impact the dosing of oral semaglutide.

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Drug Interactions With Oral Semaglutide

This video reviews potential drug-drug interactions with oral semaglutide.

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Oral Semaglutide vs. Placebo in Drug-Naïve Adults (PIONEER 1 Study)

This video discusses the trial-design and outcomes of the PIONEER 1 study. PIONEER 1 was a 26-week, phase 3a, randomized, double-blind, parallel group, multinational trial in 703 adult patients with type 2 diabetes managed with diet and exercise alone.

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Oral Semaglutide 14 mg vs. Empagliflozin 25 mg (PIONEER 2 Study)

This video discusses the trial-design and outcomes of the PIONEER 2 study. PIONEER 2 was a 52-week, phase 3a, randomized, open-label, multinational trial enrolling 822 adults with type 2 diabetes.

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Oral Semaglutide vs. Sitagliptin 100 mg (PIONEER 3 Study)

This video discusses the trial-design and outcomes of the PIONEER 3 study. PIONEER 3 was a 78-week, phase 3a, randomized, double-blind, double-dummy, multinational trial enrolling 1864 adults with type 2 diabetes.

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Oral Semaglutide 14 mg vs. Liraglutide 1.8 mg vs. Placebo (PIONEER 4 Study)

This video discusses the trial-design and outcomes of the PIONEER 4 study. PIONEER 4 was a 52-week, phase 3a, randomized, double-blind, double-dummy, active- and placebo-controlled, multinational trial in 711 adults with type 2 diabetes.

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Oral Semaglutide 14 mg vs. Placebo in Adults with Moderate Renal Impairment (PIONEER 5 Study)

This video discusses the trial-design and outcomes of the PIONEER 5 study. PIONEER 5 was a 26-week, phase 3a, randomized, double-blind, multinational trial enrolling 324 adults with type 2 diabetes and moderate renal impairment.

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Cardiovascular Safety of Oral Semaglutide vs. Placebo (PIONEER 6 Study)

This video discusses the trial-design and outcomes of the PIONEER 6 study. PIONEER 6 was a phase 3a, randomized, double-blind, multinational trial that enrolled 3183 adult patients (age ≥50 years) with type 2 diabetes. Eligible patients were at least 50 years of age with established cardiovascular (CV) disease or chronic kidney disease, or patients were at least 60 years of age with at least one CV risk factor.

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Flexible Dosing of Oral Semaglutide vs. Sitagliptin 100 mg (PIONEER 7 Study)

This video discusses the trial-design and outcomes of the PIONEER 7 study. PIONEER 7 was a 52-week, phase 3a, randomized, open-label, multinational trial with a 52-week extension enrolling 504 adults with type 2 diabetes.

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Oral Semaglutide vs. Placebo as Add-on to Insulin (PIONEER 8 Study)

This video discusses the trial-design and outcomes of the PIONEER 8 study. PIONEER 8 was a 52-week, phase 3a, randomized, double-blind, parallel-group, multinational trial enrolling 731 adults with type 2 diabetes.

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